Basic Science

Basic science advances continue across the breadth of gastroenterology research, but two areas in particular have seen significant recent advances. Studies of the microbiome and research into cell plasticity are moving from earlier descriptive work to more functional progress, according to Mark R. Frey, PhD, co-chair of the AGA Basic Science Program Committee.

Two new strategies are emerging to treat GI and other cancers — engineered T cells and immune checkpoint blockade treatments.

Gut microbiome studies have powered their way to the top of basic gastroenterology science, expanding the understanding of how the microbiome can interact with epithelial