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Featured Abstracts: Sunday, May 3

It’s day two of the Digestive Disease Week® (DDW) 2020 ePosters and ePapers site! We’ll be refreshing the content here until May 5 to bring you summaries of cutting-edge science. And don’t forget to tell us what you think using #DDW2020 on Twitter.

Abstract 564An inflammatory diet and risk of Crohn’s disease and ulcerative colitis: A prospective cohort study 

Chun-Han LoMD, postdoctoral research fellow, department of epidemiology, Harvard T.H. Chan School of Public Health, Cambridge, MA

Researchers collected data from 204,055 women and men, followed over 24-30 years, who participated in the Nurses’ Health Study, Nurses’ Health Study II and Health Professionals Follow-up Study. Dietary information was gathered using food questionnaires every four years. Researchers used the empirical dietary inflammatory pattern (EDIP) score to evaluate diets based on 18 food groups. Participants who had the highest EDIP score (more inflammatory diet) had a 45 percent increased risk of Crohn’s disease. Additionally, people who switched to a more inflammatory diet had an increase in risk of incident Crohn’s disease, suggesting a dynamic effect of diet on disease risk. However, the high inflammatory diet was not associated with risk of incident ulcerative colitis.   

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Abstract 404Risk of post-colonoscopy irritable bowel syndrome in patients with and without antibiotic exposure 

Ravy K. Vajravelu, MD, MSCE, instructor of medicine, division of gastroenterology; faculty fellow, Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia 

This retrospective cohort study analyzed more than 402,000 individuals age 50 and older enrolled in a database from 2000-2016 who underwent colonoscopy. Researchers sought to assess whether the bowel cleansing for colonoscopy in conjunction with antibiotic exposure within 14 days before or 14 days after the procedure resulted in the later diagnosis of irritable bowel syndrome (IBS) or IBS-related symptoms. The study found that antibiotic exposure within 14 days after a screening colonoscopy was associated with an increased likelihood of subsequent IBS diagnoses. 

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